Engineered apoptotic bodies hitchhiking across the blood-brain barrier achieved a combined photothermal-chemotherapeutic effect against glioma
Yu Liu, Dehong Hu, Duyang Gao, Ping Gong, Hairong Zheng, Minjie Sun, Zonghai Sheng
Abstract
This study presents engineered drug carriers with the ability to hitchhike across the BBB, providing new opportunities for the treatment of glioma.
Topics & Concepts
GliomaPhotothermal therapyIn vivoIndocyanine greenDoxorubicinBlood–brain barrierApoptosisDrug deliveryConfocal microscopyChemistryCancer researchPharmacologyMedicinePathologyChemotherapyBiologyMaterials scienceNanotechnologyCell biologySurgeryCentral nervous systemInternal medicineBiochemistryBiotechnologyOrganic chemistryNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryExtracellular vesicles in disease