Immobilization of carbonic anhydrase on modified PES membranes for artificial lungs
Yi Wang, Chong Cheng, Shuang Li, Shudong Sun, Changsheng Zhao
Abstract
in water and blood, which demonstrates the special catalytic activity towards bicarbonate of CA. Finally, blood compatibility tests prove that the CA-M does not lead to hemolysis, shows suppressed protein adsorption and increased coagulation time, and is suitable for application in ECMO. This work demonstrates a green and efficient method for preparing bioactive materials and has practical guiding significance for subsequent pulmonary membrane research and ECMO applications.
Topics & Concepts
MembraneCarbonic anhydraseCarbonic anhydrase IIChemical engineeringCompatibility (geochemistry)CatalysisMaterials scienceChemistryBiochemistryEnzymeEngineeringMechanical Circulatory Support DevicesFuel Cells and Related MaterialsMembrane-based Ion Separation Techniques