Esketamine is neuroprotective against traumatic brain injury through its modulation of autophagy and oxidative stress via AMPK/mTOR-dependent TFEB nuclear translocation
Tang Yanbin, Yufang Liu, Huanzhu Zhou, Haibo Lu, Yafei Zhang, Jun Hua, Xingzhi Liao
Topics & Concepts
AutophagyTFEBNeuroprotectionAMPKOxidative stressPI3K/AKT/mTOR pathwayNeuroscienceMedicineChemistryKinaseCell biologyProtein kinase ASignal transductionBiologyInternal medicineBiochemistryApoptosisAutophagy in Disease and TherapyCannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research