Combining Phage Display Technology with <i>In Silico</i> -Designed Epitope Vaccine to Elicit Robust Antibody Responses against Emerging Pathogen Tilapia Lake Virus
Yu‐Ming Gong, Xuefeng Wei, Yuying Zheng, Yang Li, Qing Yu, Pengfei Li, Bin Zhu
Abstract
-specific antibodies were essential for neutralizing TiLV. Our study demonstrated a model for combining experimental and computational screens to identify antigen epitopes, which is attractive for epitope-based vaccine development.
Topics & Concepts
BiologyEpitopeVirologyMimotopeAntigenAntibodyImmunologyViral Infectious Diseases and Gene Expression in InsectsBacteriophages and microbial interactionsvaccines and immunoinformatics approaches