Amylases in the Human Vagina
Kenetta L. Nunn, Gérémy Clair, Joshua Adkins, Kristin Engbrecht, Thomas Fillmore, Larry J. Forney
Abstract
In this study, we show that multiple bacteria in the vaginal community produce amylases that hydrolyze glycogen into simpler sugars (i.e., maltose and maltotriose). These sugars serve as "common goods" that sustain bacterial populations in vaginal communities. Given the temporal changes that are observed in the human vaginal microbiome, we expect the kinds of bacterial amylases produced will also vary over time. These differences influence the pool of resources that are broadly shared and shape the species composition of the vaginal bacterial community.
Topics & Concepts
MaltotrioseMaltoseVaginaAmylaseGlycogenBacteriaHydrolysisMicrobiologyBiologyFood scienceChemistryBiochemistryEnzymeAnatomyGeneticsReproductive tract infections researchUrinary Tract Infections ManagementSyphilis Diagnosis and Treatment