Litcius/Paper detail

Amylases in the Human Vagina

Kenetta L. Nunn, Gérémy Clair, Joshua Adkins, Kristin Engbrecht, Thomas Fillmore, Larry J. Forney

2020mSphere50 citationsDOIOpen Access PDF

Abstract

In this study, we show that multiple bacteria in the vaginal community produce amylases that hydrolyze glycogen into simpler sugars (i.e., maltose and maltotriose). These sugars serve as "common goods" that sustain bacterial populations in vaginal communities. Given the temporal changes that are observed in the human vaginal microbiome, we expect the kinds of bacterial amylases produced will also vary over time. These differences influence the pool of resources that are broadly shared and shape the species composition of the vaginal bacterial community.

Topics & Concepts

MaltotrioseMaltoseVaginaAmylaseGlycogenBacteriaHydrolysisMicrobiologyBiologyFood scienceChemistryBiochemistryEnzymeAnatomyGeneticsReproductive tract infections researchUrinary Tract Infections ManagementSyphilis Diagnosis and Treatment