Proteomic and lipidomic analysis of the mechanism underlying astragaloside IV in mitigating ferroptosis through hypoxia-inducible factor 1α/heme oxygenase 1 pathway in renal tubular epithelial cells in diabetic kidney disease
Jun Liu, Jing Ren, Linlan Zhou, Kaiyue Tan, Donglin Du, Lei Xu, Wenfu Cao, Yudi Zhang
Topics & Concepts
Lipid metabolismMetabolomicsHeme oxygenaseKidneyPharmacologyChemistryMetabolismDownregulation and upregulationHypoxia (environmental)Hypoxia-inducible factorsMedicineBiochemistryHemeBioinformaticsBiologyInternal medicineEnzymeOxygenGeneOrganic chemistryFerroptosis and cancer prognosisInflammasome and immune disordersTraditional Chinese Medicine Analysis