New coumarin linked thiazole derivatives as antimycobacterial agents: Design, synthesis, enoyl acyl carrier protein reductase (InhA) inhibition and molecular modeling
Asmaa F. Kassem, Ahmed Sabt, Małgorzata Korycka‐Machała, Moataz A. Shaldam, Malwina Kawka, Bożena Dziadek, Magdalena Kuzioła, Jarosław Dziadek, Rasha Z. Batran, Rasha Z. Batran
Topics & Concepts
INHAChemistryAntimycobacterialThiazoleMycobacterium tuberculosisReductaseBiochemistryCoumarinEnzymeActive siteStereochemistryTuberculosisOrganic chemistryPathologyMedicineTuberculosis Research and EpidemiologyAntimicrobial agents and applicationsComputational Drug Discovery Methods