Dendritic cells can prime anti-tumor CD8+ T cell responses through major histocompatibility complex cross-dressing
Brendan W. MacNabb, Xiufen Chen, Sravya Tumuluru, James Godfrey, Darshan N. Kasal, Jovian Yu, Marlieke L.M. Jongsma, Robbert M. Spaapen, Douglas E. Kline, Justin Kline
Topics & Concepts
Major histocompatibility complexCross-presentationBiologyCD8Antigen presentationAntigenCytotoxic T cellImmunologyMHC class IMechanism (biology)Dendritic cellAntigen-presenting cellT cellCell biologyMHC restrictionImmune systemGeneticsIn vitroPhilosophyEpistemologyImmunotherapy and Immune ResponsesT-cell and B-cell ImmunologyImmune Cell Function and Interaction