Therapeutic implications of the metabolic changes associated with BRAF inhibition in melanoma
Alexander W. Loftus, Mehrdad Zarei, Hanna Kakish, Omid Hajihassani, Jonathan J. Hue, Christina Boutros, Hallie J. Graor, Faith Nakazzi, Tsegaw Bahlibi, Jordan M. Winter, Luke D. Rothermel
Topics & Concepts
MelanomaCancer researchMedicineGlutaminolysisTargeted therapyReprogrammingMetabolic pathwayAnaerobic glycolysisGlycolysisSynthetic lethalityCancerCancer cellBiologyMetabolismCellDNA repairInternal medicineGeneticsGeneMelanoma and MAPK PathwaysHistone Deacetylase Inhibitors ResearchColorectal Cancer Treatments and Studies