Single-cell susceptibility to viral infection is driven by variable cell states
Sam Reffsin, Jesse Miller, Kasirajan Ayyanathan, Margaret C. Dunagin, Yael Heyman, Naveen Jain, D. Schultz, Sara Cherry, Arjun Raj
Topics & Concepts
BiologyVirologyViral infectionCellclone (Java method)VirusCell typeViral entryHost (biology)ImmunologyViral replicationViral sheddingGene expression profilingViral pathogenesisImmune systemPhenotypeViral loadArenavirusCell cultureCell biologyGeneticsInfluenza A virusGene expressionOrthomyxoviridaeGeneHEK 293 cellsViral diseaseSARS-CoV-2 and COVID-19 ResearchSingle-cell and spatial transcriptomicsinterferon and immune responses