Recent development of analytical methods for disease-specific protein<i>O</i>-GlcNAcylation
Wenhua Hu, Guolin Zhang, Yu Zhou, Jun Xia, Peng Zhang, Wenjin Xiao, Man Xue, Zhaohui Lu, Shuang Yang
Abstract
The enzymatic modification of protein serine or threonine residues by N -acetylglucosamine, namely O -GlcNAcylation, is a ubiquitous post-translational modification that frequently occurs in the nucleus and cytoplasm.
Topics & Concepts
Computational biologyChemistryBiologyGlycosylation and Glycoproteins ResearchGalectins and Cancer BiologyCarbohydrate Chemistry and Synthesis