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Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study

E. Geoffrey Playford, Trent P. Munro, Stephen M. Mahler, Suzanne Elliott, Michael Gerometta, Kym Hoger, Martina L. Jones, Paul Griffin, Kathleen D. Lynch, Heidi Carroll, Debra El Saadi, Margaret E. Gilmour, Benjamin Hughes, Karen Hughes, Edwin Huang, Christopher J. de Bakker, Reuben Klein, Mark G. Scher, Ina Smith, Lin‐Fa Wang, Stephen B. Lambert, Dimiter S. Dimitrov, Peter P. Gray, Christopher C. Broder

2020The Lancet Infectious Diseases149 citationsDOIOpen Access PDF

Topics & Concepts

ImmunogenicityPharmacokineticsMonoclonal antibodyTolerabilityMedicinePharmacologyGlycoproteinAntibodyImmunologyAdverse effectChemistryBiochemistryVirology and Viral Diseasesvaccines and immunoinformatics approachesParasitic Diseases Research and Treatment
Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study | Litcius