A roadmap to precision medicine through post-genomic electronic medical records
Kevin Mendez, Stacey N. Reinke, Rachel S. Kelly, Qingwen Chen, Mark K. Su, Michael J. McGeachie, Scott T. Weiss, David Broadhurst, Jessica Lasky‐Su
Abstract
The promise of integrating Electronic Medical Records (EMR) and genetic data for precision medicine has largely fallen short due to its omission of environmental context over time. Post-genomic data can bridge this gap by capturing the real-time dynamic relationship between underlying genetics and the environment. This perspective highlights the pivotal role of integrating EMR and post-genomics for personalized health, reflecting on lessons from past efforts, and outlining a roadmap of challenges and opportunities that must be addressed to realize the potential of precision medicine. The authors outline a framework uniting electronic medical records with post-genomic data to capture real-time physiological changes via periodic molecular snapshots, enabling a shift from reactive treatments to proactive, inclusive care.