Litcius/Paper detail

Role of distal arginine residue in the mechanism of heme nitrite reductases

Ankita Sarkar, Snehadri Bhakta, Samir Chattopadhyay, Abhishek Dey

2023Chemical Science13 citationsDOIOpen Access PDF

Abstract

Influence of the protonation state of the guanidinium group, present in the 2nd sphere of an iron porphyrin complex, in the reduction of nitrite to nitric oxide via {FeNO} 6 intermediate.

Topics & Concepts

NitriteProtonationHemeChemistryPorphyrinResidue (chemistry)ArginineNitric oxideNitrite reductaseHemeproteinBiochemistryStereochemistryPhotochemistryAmino acidEnzymeOrganic chemistryIonNitrateHemoglobin structure and functionNitric Oxide and Endothelin EffectsHeme Oxygenase-1 and Carbon Monoxide