Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility
Christopher A. Koczor, Marlo K. Thompson, Nidhi Sharma, Aishwarya Prakash, Robert W. Sobol
Topics & Concepts
BiologyXRCC1Base excision repairProcessivityDNA repairDNA polymeraseDNA damageDNA polymerase betaMolecular biologyCell biologyDNAGeneticsGeneGenotypeSingle-nucleotide polymorphismDNA Repair MechanismsPARP inhibition in cancer therapyGenomics and Chromatin Dynamics