Litcius/Paper detail

Proton Pump Inhibitors (PPI)

Abdelwahab Ahmed, John O. Clarke

2021StatPearls13 citations

Abstract

Proton pump inhibitors represent a class of medications used to treat a wide variety of pathologies related to the stomach's acid production. This activity reviews the indications, action, contraindications for proton pump inhibitors as a valuable agent in managing acid-related disorders. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the interprofessional team in the treatment of acid-related disorders.

Topics & Concepts

DosingPharmacodynamicsProton-pump inhibitorAdverse effectPharmacologyMedicineMechanism of actionPharmacokineticsIntensive care medicineChemistryBiochemistryInternal medicineIn vitroGastroesophageal reflux and treatmentsHelicobacter pylori-related gastroenterology studiesPotassium and Related Disorders