Recent advances in the synthesis of 2,3-dihydropyrroles
Dong Wang, Yu Fan, Peng Yu, Laurent Désaubry
Abstract
The 2,3-dihydropyrrole unit is a privileged heterocycle found in many pharmacologically active natural products. Significant recent advances in the synthesis of this heterocycle have led to intense interest in the development of new drug candidates. The aim of this review is to summarize advances accomplished in this stimulating field with an emphasis on recent developments or important seminal contributions.
Topics & Concepts
Engineering ethicsDrug discoveryComputer scienceCombinatorial chemistryNanotechnologyBiochemical engineeringChemistryEngineeringMaterials scienceBiochemistrySynthesis and Characterization of PyrrolesAsymmetric Synthesis and CatalysisSynthesis and pharmacology of benzodiazepine derivatives