Dual role of macrophages in skeletal muscle atrophy: Mechanisms and therapeutic strategies
Tongxin Shang, XU Hong-yi, Xinlei Yao, Zihao Zhao, Xinxin Niu, Yuntian Shen, Bingqian Chen, Hualin Sun
Topics & Concepts
Skeletal muscleInflammationCell biologyBiologyMacrophage polarizationMuscle atrophyImmune systemTumor necrosis factor alphaInnate immune systemMyocyteRegeneration (biology)AutophagyTranscription factorProgenitor cellSTAT proteinMacrophageMuscle hypertrophyHomeostasisMyogenesisCellProinflammatory cytokinestatAtrophyCytoprotectionChemokineSarcopeniaCancer researchStem cellCytokineCell growthIntracellularNeuroscienceImmunologyProtein degradationDual roleDownregulation and upregulationMuscle Physiology and DisordersExercise and Physiological ResponsesNutrition and Health in Aging