Effect of respiratory rate and size of cannula on pressure and dead-space clearance during nasal high flow in patients with COPD and acute respiratory failure
Maximilian I. Pinkham, U Domanski, Karl-Josef Franke, Justus Hartmann, Maik Schroeder, T. Williams, Georg Nilius, Stanislav Tatkov
Abstract
During nasal high flow (NHF) an increased breathing frequency, which is commonly observed in acute respiratory failure, can lead to decreased dead-space clearance. Higher NHF rates increase the clearance and reduce the rebreathing which may eventually lower the respiratory rate and the work of breathing. Monitoring of the respiratory rate could be an important indicator of not only the respiratory function but also the NHF rate selection and the therapy efficacy.
Topics & Concepts
Dead spaceMedicineAnesthesiaCannulaExpirationRespiratory rateRespiratory systemNasal cannulaVentilation (architecture)COPDRespiratory failureMechanical ventilationInternal medicineSurgeryHeart rateBlood pressureMechanical engineeringEngineeringRespiratory Support and MechanismsAirway Management and Intubation TechniquesInhalation and Respiratory Drug Delivery