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Linagliptin mitigates cisplatin-induced kidney impairment via mitophagy regulation in rats, with emphasis on SIRT-3/PGC-1α, PINK-1 and Parkin-2

Mohamed G. Ewees, Gomaa Mostafa-Hadeab, Sameh Saber, Eman Ali Abd El‐Meguid, Haidy T. Abo Sree, Fatema El-Zahraa S. Abdel Rahman, Nesreen Ishak Mahmoud

2024Toxicology and Applied Pharmacology12 citationsDOI

Topics & Concepts

LinagliptinMitophagyParkinKidneyPharmacologyMedicineDiabetes mellitusCisplatinOxidative stressInternal medicineCancer researchAutophagyEndocrinologyBiologyType 2 diabetesChemotherapyApoptosisBiochemistryParkinson's diseaseDiseaseChemotherapy-induced organ toxicity mitigationNeurological Complications and SyndromesPharmacological Effects and Toxicity Studies
Linagliptin mitigates cisplatin-induced kidney impairment via mitophagy regulation in rats, with emphasis on SIRT-3/PGC-1α, PINK-1 and Parkin-2 | Litcius