Near‐infrared light-triggered nitric oxide nanocomposites for photodynamic/photothermal complementary therapy against periodontal biofilm in an animal model
Xiangrong Wu, Manlin Qi, Chengyu Liu, Qijing Yang, Sijia Li, Fangyu Shi, Xiaolin Sun, Lin Wang, Chunyan Li, Biao Dong
Abstract
: We successfully prepared a novel nanocomposite with NO synergistic aPTT and aPDT. It had an outstanding therapeutic effect in treating deep tissue biofilm infection. This study not only enriches the research on compound therapy with NO gas therapy but also provides a new solution for other biofilm infection diseases.
Topics & Concepts
BiofilmIn vivoChemistryPhotodynamic therapyPhotothermal therapyStainingNitric oxideDental plaqueMicrobiologyMaterials sciencePathologyNanotechnologyMedicineBacteriaBiologyGeneticsBiotechnologyOrganic chemistryOral microbiology and periodontitis researchNanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies