Insights into the chiral sulfide/selenide-catalyzed electrophilic carbothiolation of alkynes: mechanism and origin of axial chirality
Qiaoyu Zhang, Shijun Li, Yang Wang, Jinshuai Song, Yu Lan, Donghui Wei
Abstract
The FMO overlap mode, ELF, and AIM analyses along the formation process of thiiranium ion intermediate have been performed for the first time to explore the nature of the electronic structural changes and origin of stereoselectivity.
Topics & Concepts
ChemistrySelenideElectrophileChirality (physics)SulfideStereoselectivityMechanism (biology)CatalysisComputational chemistryStereochemistryOrganic chemistrySeleniumParticle physicsNambu–Jona-Lasinio modelPhysicsChiral symmetry breakingPhilosophyQuarkEpistemologyAxial and Atropisomeric Chirality SynthesisSulfur-Based Synthesis TechniquesOrganoselenium and organotellurium chemistry