An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia
Jeevisha Bajaj, Michael Hamilton, Yutaka Shima, Kendall R. Chambers, Kyle Spinler, Eric L. Van Nostrand, Brian A. Yee, Steven M. Blue, Michael Chen, David Rizzeri, Charles Chuah, Vivian G. Oehler, H. Elizabeth Broome, Roman Šášik, James Scott‐Browne, Anjana Rao, G Yeo, Tannishtha Reya
Topics & Concepts
Myeloid leukemiaLeukemiaRegulatorBiologyMyeloidCRISPRCancer researchChromatinImmunologyGeneticsGeneRNA Research and SplicingGenomics and Chromatin DynamicsRNA and protein synthesis mechanisms