Activation of the Two-Component System LisRK Promotes Cell Adhesion and High Ampicillin Tolerance in Listeria monocytogenes
Hüsnü Aslan, Maiken Engelbrecht Petersen, Alberto De Berardinis, Maja Z Brunhede, Nasar Khan, Alberto Vergara, Birgitte H. Kallipolitis, Rikke Louise Meyer
Abstract
mutant. The same protection was not offered to other antibiotics (vancomycin, gentamicin, tetracycline), and the mechanism for antibiotic tolerance is thus highly specific. Furthermore, quantification of bacterial attachment rates and attachment force also revealed that the absence of a functional LisRK rendered the cells less adhesive. Hence, LisRK TCS promotes multiple protective mechanisms simultaneously.
Topics & Concepts
Listeria monocytogenesAmpicillinListeriaMicrobiologyAdhesionComponent (thermodynamics)ChemistryBacteriaBiologyAntibioticsGeneticsOrganic chemistryThermodynamicsPhysicsListeria monocytogenes in Food SafetyMicrobial Inactivation MethodsEssential Oils and Antimicrobial Activity