SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects
Matthew D. Durbin, J. P. O’Kane, Samuel G Lorentz, Anthony B. Firulli, Stephanie M. Ware
Topics & Concepts
BiologyDishevelledWnt signaling pathwayCell biologyPhenocopyHeart developmentInterventricular septumZebrafishVentricleInternal medicineSignal transductionPhenotypeGeneticsGeneFrizzledEmbryonic stem cellMedicineCongenital heart defects researchWnt/β-catenin signaling in development and cancerRenal and related cancers