TRPM2, linking oxidative stress and Ca2+ permeation to NLRP3 inflammasome activation
Longfei Wang, Roberto Negro, Hao Wu
Topics & Concepts
InflammasomePyroptosisTRPM2Cell biologyReactive oxygen speciesOxidative stressChemistryInnate immune systemInflammationCaspase 1EffectorCalcium signalingImmune systemIntracellularBiologyImmunologyBiochemistryTransient receptor potential channelReceptorInflammasome and immune disordersIon Channels and ReceptorsHeme Oxygenase-1 and Carbon Monoxide