Photoredox trifluoromethylation of isocyanides to access 2-trifluoromethylated quinolines and indoles
Jin Wang, Yaohui Liu, Jinhai Xu, Peiyuan Li, Xiaoxi Xu, Xiaoxi Xu, Shuo Zhang, Jie Yang, Xianxiu Xu, Xianxiu Xu
Abstract
We herein report a divergent synthesis of 2-CF 3 substituted quinolines and indoles via photoredox radical trifluoromethylation of ortho -vinylphenylisocyanides.
Topics & Concepts
TrifluoromethylationChemistryCombinatorial chemistryMedicinal chemistryOrganic chemistryTrifluoromethylAlkylFluorine in Organic Chemistry