Novel smac mimetic ASTX660 (Tolinapant) and TNF-α synergistically induce necroptosis in bladder cancer cells in vitro upon apoptosis inhibition
Lei Wang, Changhua Hu, Yu Zhao, Xiaoquan Hu
Topics & Concepts
NecroptosisApoptosisProgrammed cell deathTumor necrosis factor alphaCaspaseCancer cellNecrosisCell biologyBiologyCancer researchIntrinsic apoptosisCancerImmunologyBiochemistryGeneticsCell death mechanisms and regulationCancer-related Molecular PathwaysHeat shock proteins research