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Bioadhesive ultrasound for long-term continuous imaging of diverse organs

Chonghe Wang, Xiaoyu Chen, Liu Wang, Mitsutoshi Makihata, Hsiao‐Chuan Liu, Tao Zhou, Xuanhe Zhao

2022Science570 citationsDOI

Abstract

Continuous imaging of internal organs over days could provide crucial information about health and diseases and enable insights into developmental biology. We report a bioadhesive ultrasound (BAUS) device that consists of a thin and rigid ultrasound probe robustly adhered to the skin via a couplant made of a soft, tough, antidehydrating, and bioadhesive hydrogel-elastomer hybrid. The BAUS device provides 48 hours of continuous imaging of diverse internal organs, including blood vessels, muscle, heart, gastrointestinal tract, diaphragm, and lung. The BAUS device could enable diagnostic and monitoring tools for various diseases.

Topics & Concepts

BioadhesiveUltrasoundBiomedical engineeringDiaphragm (acoustics)HindgutMedicineRadiologyMaterials scienceBiologyDrug deliveryNanotechnologyAcousticsLoudspeakerPhysicsMidgutLarvaBotanyAdvanced Sensor and Energy Harvesting MaterialsElectrical and Bioimpedance TomographyPhotoacoustic and Ultrasonic Imaging
Bioadhesive ultrasound for long-term continuous imaging of diverse organs | Litcius