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Structure-activity relationship analysis of perfluoroalkyl carbonic acids on human and rat placental 3β-hydroxysteroid dehydrogenase activity

Shaowei Wang, Bingru Zhang, Yingna Zhai, Yunbing Tang, Yuzhen Lou, Yang Zhu, Yiyan Wang, Ren‐Shan Ge, Huitao Li

2022Toxicology40 citationsDOI

Topics & Concepts

ChemistryPregnenoloneDehydrogenaseSteroidStereochemistryPregnanoloneInternal medicineIC50EndocrinologyBiochemistryEnzymeNeuroactive steroidIn vitroHormoneReceptorBiologyMedicineGABAA receptorPer- and polyfluoroalkyl substances researchBirth, Development, and HealthEffects and risks of endocrine disrupting chemicals
Structure-activity relationship analysis of perfluoroalkyl carbonic acids on human and rat placental 3β-hydroxysteroid dehydrogenase activity | Litcius