Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors
Kunal Nepali, Ting-Yu Chang, Mei-Jung Lai, Kai‐Cheng Hsu, Yun Yen, Tony Eight Lin, Sung‐Bau Lee, Jing‐Ping Liou
Topics & Concepts
BenzamideChemistryIC50Histone deacetylaseCytotoxicityCell culturePharmacologyHistone deacetylase inhibitorCancer cellIn vitroHDAC1PurineStereochemistryBiochemistryCancerEnzymeHistoneBiologyGeneGeneticsHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsPeptidase Inhibition and Analysis