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Design and synthesis of methoxyphenyl- and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS-induced RAW264.7 macrophage cells

Soha H. Emam, Amr Sonousi, Eman O. Osman, Dukhyun Hwang, Gun‐Do Kim, Rasha A. Hassan

2021Bioorganic Chemistry84 citationsDOI

Topics & Concepts

CoumarinChalconeChemistryNitric oxideAnti-inflammatoryNitric oxide synthaseEnzymePharmacologyLipopolysaccharideBiochemistryNF-κBStereochemistryApoptosisImmunologyOrganic chemistryBiologyMedicineSynthesis and biological activityGenomics, phytochemicals, and oxidative stressNatural product bioactivities and synthesis
Design and synthesis of methoxyphenyl- and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS-induced RAW264.7 macrophage cells | Litcius