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Nascent alt-protein chemoproteomics reveals a pre-60S assembly checkpoint inhibitor

Xiongwen Cao, Alexandra Khitun, Cecelia M. Harold, Carson J. Bryant, Shu-Jian Zheng, Susan J. Baserga, Sarah A. Slavoff

2022Nature Chemical Biology32 citationsDOIOpen Access PDF

Topics & Concepts

Ribosomal proteinProtein subunitCell biologyDownregulation and upregulationF-box proteinBiologyEukaryotic Large Ribosomal SubunitCell Cycle ProteinCytoplasmEukaryotic Small Ribosomal SubunitCell cycleRibosomal RNAChemistryCellUbiquitinBiochemistryRibosomeGeneRNAUbiquitin ligase18S ribosomal RNAPeptidase Inhibition and AnalysisRNA and protein synthesis mechanismsUbiquitin and proteasome pathways
Nascent alt-protein chemoproteomics reveals a pre-60S assembly checkpoint inhibitor | Litcius