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Discovery of benzimidazole substituted 1, 2, 4-oxadiazole compounds as novel anti-HBV agents with TLR8-agonistic activities

Jingying Qiu, Yueting Zou, Shuqiong Li, Lihua Yang, Zi‐Bin Qiu, Fanyun Kong, Xiaoke Gu

2022European Journal of Medicinal Chemistry18 citationsDOI

Topics & Concepts

ChemistryBenzimidazoleIC50Hepatitis B virusIn vitroIn vivoImmune systemLuciferasePharmacologyStereochemistryVirologyVirusBiochemistryImmunologyTransfectionGeneBiologyBiotechnologyOrganic chemistryHepatitis B Virus StudiesNF-κB Signaling PathwaysRNA Interference and Gene Delivery
Discovery of benzimidazole substituted 1, 2, 4-oxadiazole compounds as novel anti-HBV agents with TLR8-agonistic activities | Litcius