Litcius/Paper detail

Respiratory Distress in SARS-CoV-2 without Lung Damage: Phrenic Paralysis Should Be Considered in COVID-19 Infection

F. Maurier, B. Godbert, Julie Perrin

2020European Journal of Case Reports in Internal Medicine31 citationsDOIOpen Access PDF

Abstract

We describe an overweight COVID-19 patient with respiratory distress preceded by anosmia/dysgeusia with no lung injury shown on CT, angio-CT or ventilation/perfusion scans. Orthopnoea and paradoxical abdominal respiration were identified. Phrenic paralysis, demonstrated by examination of patient breathing, and on x-ray while standing breathing in and out, explained the respiratory distress. This is a rare and previously undescribed neurological complication of COVID-19 infection caused by vagus nerve injury. LEARNING POINTS: Phrenic paralysis must be kept in mind as a rare neurological complication of COVID-19.Vagus nerve palsy is a neurological manifestation as anosmia and dysgeusia, that were already identified in the olfactory system of COVID-19 patients.

Topics & Concepts

MedicineAnosmiaParalysisAnesthesiaRespiratory distressDysgeusiaVentilation (architecture)Coronavirus disease 2019 (COVID-19)LungPhrenic nerveRespiratory systemSurgeryInternal medicineAdverse effectEngineeringDiseaseMechanical engineeringInfectious disease (medical specialty)Long-Term Effects of COVID-19Respiratory and Cough-Related ResearchAutoimmune Neurological Disorders and Treatments