Litcius/Paper detail

Advances in Nanoliposomes for the Diagnosis and Treatment of Liver Cancer

Yitong Li, Ruihang Zhang, Zhen Xu, Zhicheng Wang

2022International Journal of Nanomedicine56 citationsDOIOpen Access PDF

Abstract

The mortality rate of liver cancer is gradually increasing worldwide due to the increasing risk factors such as fatty liver, diabetes, and alcoholic cirrhosis. The diagnostic methods of liver cancer include ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI), among others. The treatment of liver cancer includes surgical resection, transplantation, ablation, and chemoembolization; however, treatment still faces multiple challenges due to its insidious development, high rate of recurrence after surgical resection, and high failure rate of transplantation. The emergence of liposomes has provided new insights into the treatment of liver cancer. Due to their excellent carrier properties and maneuverability, liposomes can be used to perform a variety of functions such as aiding in imaging diagnoses, combinatorial therapies, and integrating disease diagnosis and treatment. In this paper, we further discuss such advantages.

Topics & Concepts

Liver cancerMedicineMagnetic resonance imagingCancerLiposomeFatty liverUltrasoundComputed tomographyRadiologyMortality rateLiver diseaseHepatocellular carcinomaDiseaseCancer treatmentUltrasonographyLiver failureCancer researchUltrasound imagingMedical imagingOncologyPathologySurvival rateInternal medicineUltrasonic imagingBiomedical engineeringCancer therapyDisease treatmentCancer imagingHepatocellular Carcinoma Treatment and PrognosisNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics