Catalytic Electrophilic Thiocarbocyclization of Allenes
Quanbin Jiang, Huimin Li, Xiaodan Zhao
Abstract
An efficient approach via catalytic electrophilic thiocarbocyclization of allenes to construct indene-based sulfides with excellent regioselectivities is disclosed. The reactions were carried out at low temperatures by selenide catalysis in the presence of TMSOTf. Not only electrophilic arylthio reagents but also electrophilic alkylthio reagents worked well under these conditions. Furthermore, the method could be applied to intermolecular azidothiolation of allenes.
Topics & Concepts
ElectrophileChemistryReagentCatalysisIndeneSelenideIntermolecular forceElectrophilic additionCombinatorial chemistryOrganic chemistryMoleculeSeleniumSulfur-Based Synthesis TechniquesCyberloafing and Workplace BehaviorChemical Synthesis and Reactions