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Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury

Weihuang Qiu, Sheng An, Tingjie Wang, Jiaxin Li, Binmei Yu, Zhenhua Zeng, Zhongqing Chen, Bo Lin, Xianzhong Lin, Youguang Gao

2022International Immunopharmacology91 citationsDOI

Topics & Concepts

GPX4MelatoninSepsisKidneyPharmacologyMalondialdehydeProgrammed cell deathChemistryOxidative stressMedicineImmunologyInternal medicineApoptosisGlutathione peroxidaseBiochemistryCatalaseFerroptosis and cancer prognosisBladder and Urothelial Cancer TreatmentsInflammasome and immune disorders
Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury | Litcius