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pH-responsive sustained delivery of doxorubicin using aminated and PEGylated mesoporous silica nanoparticles leads to enhanced antitumor efficacy in pre-clinical orthotopic breast cancer model

Arijit Mal, Prabhuraj R.S., Renu Malhotra, Snehal K. Valvi, Arvind Ingle, Rohit Srivastava, Abhijit De, Rajdip Bandyopadhyaya

2022Journal of Drug Delivery Science and Technology21 citationsDOI

Topics & Concepts

DoxorubicinMesoporous silicaHyaluronic acidCytotoxicityPEG ratioChemistryPolyethylene glycolPharmacologyPEGylationDrug deliveryToxicityMaterials scienceChemotherapyIn vitroMedicineMesoporous materialBiochemistrySurgeryOrganic chemistryCatalysisEconomicsFinanceAnatomyNanoparticle-Based Drug DeliveryChemotherapy-induced cardiotoxicity and mitigationCancer Treatment and Pharmacology
pH-responsive sustained delivery of doxorubicin using aminated and PEGylated mesoporous silica nanoparticles leads to enhanced antitumor efficacy in pre-clinical orthotopic breast cancer model | Litcius