Catalyst-free C–N bond formation under biocompatible reaction conditions
Jeffrey Goh, Seng Kheong Ong, Yan Sheng Tan, Teck‐Peng Loh
Abstract
A C–N bond formation reaction under benign conditions for the amination of allenic ketones to access enaminones is reported. This reaction is atom economical, green, highly regioselective and works well with many structurally crucial amines.
Topics & Concepts
RegioselectivityAminationCatalysisChemistryAtom economyReaction conditionsCombinatorial chemistryBiocompatible materialOrganic chemistryMedicineBiomedical engineeringSynthesis and Catalytic ReactionsAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization Methods