Litcius/Paper detail

The Affordability of Guideline-Directed Medical Therapy

Alexander T. Sandhu, Paul A. Heidenreich

2021Circulation31 citationsDOIOpen Access PDF

Abstract

Heart failure with reduced ejection fraction has seen remarkable advances with multiple medical therapies that reduce mortality. Despite these breakthroughs, guideline-recommended medical therapy (GDMT) is underutilized. The reasons for suboptimal implementation are manifold but surmountable. These include gaps in clinician knowledge, patient reluctance to take chronic medications, clinical inertia, and, increasingly, GDMT affordability.

Topics & Concepts

MedicineGuidelineIntensive care medicineMedical therapyInternal medicinePathologyMedication Adherence and CompliancePharmaceutical Economics and PolicyHealth Systems, Economic Evaluations, Quality of Life