One-pot synthesis of novel poly-substituted 3-cyanopyridines: Molecular docking, antimicrobial, cytotoxicity, and DFT/TD-DFT studies
Islam M. Abdellah, Mohamed R. Eletmany, Antar A. Abdelhamid, Haitham S. Alghamdi, Ashraf N. Abdalla, Ahmed A. Elhenawy, Fawy M. Abd El Latif
Topics & Concepts
ChemistryMalononitrileDocking (animal)PyridineCytotoxicityMTT assayStereochemistryIC50Alkoxy groupActive siteCombinatorial chemistryCell growthEnzymeMedicinal chemistryIn vitroOrganic chemistryBiochemistryAlkylNursingCatalysisMedicineSynthesis and biological activityMulticomponent Synthesis of HeterocyclesSynthesis and Characterization of Heterocyclic Compounds