Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms
Xiaowei Liu, Hao-Wei Xu, Yu‐Yang Yi, Shu‐Bao Zhang, Sheng-Jie Chang, Wei Pan, Shan‐Jin Wang
Topics & Concepts
SenescenceOsteoblastOsteoporosisGene knockdownInternal medicineBone marrowCell biologyEndocrinologyPeak bone massChemistryBiologyBone massApoptosisMedicineBiochemistryIn vitroRNA modifications and cancerMicroRNA in disease regulationPeptidase Inhibition and Analysis