Luminescent lanthanide nanoparticle-based imaging enables ultra-sensitive, quantitative and multiplexed <i>in vitro</i> lateral flow immunoassays
Fanny Mousseau, Cécile Feraudet‐Tarisse, Stéphanie Simon, Thierry Gacoin, Antigoni Alexandrou, Cédric Bouzigues
Abstract
We developed a portable, fast, highly sensitive and quantitative in vitro assay for on-site biomolecule detection by combining the remarkable optical properties of new lanthanide-doped nanoparticle probes with a simple reader coupled to a smartphone.
Topics & Concepts
LanthanideBiomoleculeLuminescenceNanoparticleMaterials scienceLuminescent MeasurementsNanotechnologyIn vitroMultiplexingChemistryOptoelectronicsComputer scienceIonTelecommunicationsOrganic chemistryBiochemistryBiosensors and Analytical DetectionAdvanced Biosensing Techniques and ApplicationsInnovative Microfluidic and Catalytic Techniques Innovation