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Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics

Yushen Huang, Wen Luo, Siyun Chen, Hongmei Su, Wuchang Zhu, Yuanyuan Wei, Yue Qiu, Yan Long, Yanxia Shi, Jinbin Wei, Jinbin Wei

2023Phytomedicine27 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayHepatic stellate cellProtein kinase BHepatic fibrosisFibrosisGlutathioneCancer researchIn vivoPharmacologyChemistrySignal transductionBiologyCell biologyMedicineBiochemistryInternal medicineEndocrinologyEnzymeBiotechnologyLiver physiology and pathologyMicroRNA in disease regulationLiver Disease Diagnosis and Treatment
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics | Litcius