Exploiting the MUC5AC Antigen for Noninvasive Identification of Pancreatic Cancer
Kelly E. Henry, Travis M. Shaffer, Kyeara N. Mack, Janine Ring, Anuja Ogirala, Susanne Klein‐Scory, Christina Eilert-Micus, Wolff Schmiegel, Thilo Bracht, Barbara Sitek, Marguerite Clyne, Colm J. Reid, Bence Sipos, Jason S. Lewis, Holger Kalthoff, Jan Grimm
Abstract
Zr-desferrioxamine-RA96 shows specific detection of MUC5AC-positive tumors in vivo, highlighting the utility of MUC5AC targeting for diagnosis of PC.
Topics & Concepts
MedicinePancreatic cancerImmunohistochemistryAntigenPancreatitisCancerPathologyAdenocarcinomaBiomarkerAntibodyBiopsyInternal medicineImmunologyBiologyBiochemistryPancreatic and Hepatic Oncology ResearchRadiopharmaceutical Chemistry and ApplicationsMedical Imaging and Pathology Studies