The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
Robert A. Saxton, Lukas T. Henneberg, Marco Calafiore, Leon Su, Kevin M. Jude, Alan M. Hanash, K. Christopher García
Topics & Concepts
BiologyAgonistInflammationCell biologySignal transductionCytokineReceptorFunctional selectivityImmunologyG protein-coupled receptorBiochemistryCytokine Signaling Pathways and InteractionsWhipple's Disease and InterleukinsIL-33, ST2, and ILC Pathways