Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila
Bradford Becken, Lauren Davey, Dustin R. Middleton, Katherine D. Mueller, Agastya Sharma, Zachary C. Holmes, Eric P. Dallow, Brenna C. Remick, Gregory M. Barton, Lawrence A. David, Jessica R. McCann, Sarah Armstrong, Per Malkus, Raphael H. Valdivia
Abstract
The abundance of Akkermansia muciniphila in the gastrointestinal (GI) tract is linked to multiple positive health outcomes. There are four known A. muciniphila phylogroups, yet the prevalence of these phylogroups and how they vary in their ability to influence human health is largely unknown.
Topics & Concepts
Akkermansia muciniphilaBiologyVerrucomicrobiaHuman gastrointestinal tractGenotypePhenotypeMicrobiologyBacteriaGeneticsGene16S ribosomal RNAActinobacteriaEnterobacteriaceae and Cronobacter ResearchCystic Fibrosis Research AdvancesInfant Nutrition and Health