Conjugative IncC Plasmid Entry Triggers the SOS Response and Promotes Effective Transfer of the Integrative Antibiotic Resistance Element SGI1
M. Pons�, Karine Praud, Sandra Da Re, Axel Cloeckaert, Benoît Doublet
Abstract
Antimicrobial resistance has become a major public health issue, particularly with the increase of multidrug resistance (MDR) in both animal and human pathogenic bacteria and with the emergence of resistance to medically important antibiotics. The spread between bacteria of successful mobile genetic elements, such as conjugative plasmids and integrative elements conferring multidrug resistance, is the main driving force in the dissemination of acquired antibiotic resistances among Gram-negative bacteria.
Topics & Concepts
PlasmidGenomic islandBiologyMultiple drug resistanceAntibiotic resistanceSalmonellaGeneticsMobile genetic elementsGeneMicrobiologyBacteriaAntibioticsSalmonella and Campylobacter epidemiologyAntibiotic Resistance in BacteriaVibrio bacteria research studies