Cholecystokinin Signaling can Rescue Cognition and Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease
Zijuan Zhang, Ziyang Yu, Ye Yuan, Jing Yang, Shijie Wang, He Ma, Hao Li, Jinlian Ma, Zhonghua Li, Zhenqiang Zhang, Christian Hölscher
Topics & Concepts
NeuroscienceSynaptic plasticityCREBNeuroprotectionTropomyosin receptor kinase BHippocampusCholecystokininSynaptogenesisSynapseCholecystokinin B receptorPI3K/AKT/mTOR pathwayBiologySignal transductionNeurotrophic factorsReceptorInternal medicineCell biologyMedicineTranscription factorGeneBiochemistryNeuropeptides and Animal PhysiologyNeuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research